Archive for the ‘Pandemic’ Category

A Cruel Wind

Wednesday, June 9th, 2010

Pettit, Dorothy A., and Janice Bailie. A Cruel Wind: Pandemic Flu in America, 1918-1920. Murfreesboro, Tenn.: Timberlane Books, 2008. RC 150.5 .A2 P48 2008

Library of Congress Image

We all know – or think we know – much about the “Great Epidemic” of flu that struck in 1918. But in this extensively researched and well-written account of the full outbreak (1918-1920), Dorothy Pettit and Janice Bailie have given us the complete story, which has implications for public health, medical research and even politics in our time.

With medical and health sciences backgrounds (as well as a Ph.D. in History and in Biochemistry), the authors bring a wealth of knowledge to their subject, resulting in a work that is technical but nonetheless accessible. Their knowledge shows in their writing; they draw from a wide cross-section of research to support their ideas. But sprinkled throughout are personal reflections and stories which further illustrate the impact of the epidemic, without distracting from the subject.

The book begins with an in-depth definition of pandemic, and influenza, as well as the symptoms, theories and causes. Throughout, detailed graphs, charts and the occasional illustration draw out explicit conclusions from the text. The links between 1918 and the present (and even the past) are also clearly detailed. What we now know is encouraging, but we still have far to go, in terms of both public health and management of the disease (including vaccination) and medical science.

Chapter 1 (“Riddle of Influenza”) grounds the reader, in the science and public health situation of the time, and explains why the 1918 epidemic was so stunning in its effects. Chapter 2 (“The Silent Foe”) highlights the beginnings of the outbreak in the spring of 1918, and focuses on the political and military backdrop against which the flu played out, as well as the spread of the disease worldwide, and the relationship of the different strains. Sanitary conditions, for example, were in some cases not much better than they had been at the end of the Civil War, and military and political leaders seemed to spend more time passing blame on each other than on improving conditions. One quote exemplifies the situation: “…each day a [nurse] came around with a dose of castor oil, using the same utensil for patient after patient.” (p. 68)

Chapter 3 (“A Kind of Plague”) details the overwhelming nature of the epidemic, illustrated by specific instances. The situation at Presbyterian Hospital in New York, for instance, was horrible: “For what seemed like an eternity, each morning when the doctors made their rounds, all of the men in the critical section would be gone, all having died during the night.” (p. 95) The role of the press in the public health situation is discussed: was it helpful, for instance, for the Washington Post to print the names and ages of the victims daily? The discussion of the closing of schools, theaters and other public places as well as the shortage of caskets give the reader an idea of the vastness of this epidemic.

Chapter 4 (“One War Ends”) continues the public health discussion, detailing how the closings impacted jobs, and how, immediately prior to Prohibition, there was a sharp uptake in the increase of alcohol (particularly whiskey) for ‘health’ purposes. The contrast between the optimism at the end of the war and the discouragement of the ongoing flu epidemic is striking, as a second wave of infections made its way around the world. Chapter 5 (“Paris Cold”) focuses on the evolution of the disease, as well as the effects of the flu on the peace treaty in Paris. The precarious health of many of the participants in the negotiations, including Colonel House (the President’s chief advisor) and the President himself, made them extremely difficult.

Chapter 6 (“The Aftermath”) details the lingering (and devastating) effects of the illness on post-war recovery, and shows how this period was, in effect, the beginning of “Public Health” as we know it:

The pandemic had a noticeable impact on both individual lives and on human institutions. It forced the government to take up the questions of support for medical research and of the relationship between public health and private medicine. There was a remarkable institutional response to the pandemic, which will be examined in this chapter. But the institutional response grew out of the desperate needs of individual victims of the pandemic. Social workers and others began to see how essential it was that communities provide certain minimum services necessary to safeguard the health of their citizens. Health matters would have to become a public rather than a private concern. (p. 177)

Chapter 7 (“A Tired Nation”) continues discussing the broader impacts of the flu. For example, the health of various Senators and Congressmen was affected, as were Native Americans; even prices for various remedies (such as lemons) increased dramatically as demand soared. (The flu’s impact on the family of poet Robert Frost is illustrative, and quotes from their letters are used throughout the book to illustrate the phases of the pandemic.) Chapter 8 (“The Battle Continues”) discusses how we know what we know today about the flu of 1918, and how it has been studied. The development of antiviral drugs (such as Tamiflu) and other remedies through specific clinical trials is also detailed.

Finally, extensive notes, bibliography and a well-done index make this book an ideal source for anyone studying the medical or public health impacts of the 1918 outbreak or, indeed, any pandemic disease.

Contagion: Historical Views of Disease and Epidemic

Wednesday, April 21st, 2010

Interested in historical accounts of diseases and the public health history of epidemics? The Contagion collection, developed by the Harvard University Library Open Collections Program, gives researchers access to a wealth of primary resources, in a format that’s as useful for browsing (and topic discovery!) as it is for hard-core research.

The collection is separated into 9 different topic areas, covering everything from the Boston Smallpox Epidemic in 1721 to the use of the term “Pestilence” in printed books of the late 15th century. In addition, browsing options abound, from a timeline of significant dates for the study of disease (1494-1948), with hyperlinked access to any content in the collection to a list of notable people (again, hyperlinked) to a “browse by material type” (texts, early printed books, images etc.) option.

Perhaps the most impressive thing about this collection is the wide range of repositories across Harvard from which materials have been drawn. Libraries at the Medical School, Business School, Law School, University and College all contributed. This means that the collection includes some fascinating, difficult-to-find materials from Asia (from the Harvard-Yenching Library) and on women in medicine (from the Arthur and Elizabeth Schlesinger Library on the History of Women in America)

In addition to the fantastic primary sources, introductory essays on a list of topics relating to the history of medicine give the researcher a window into what early doctors and public health professionals thought about, for instance, “Humoral Theory“. These essays include links to relevant materials within the collection, as well as a brief bibliography of resources for further study. The introductory essay topics are:

Colonialism and International Medicine
Concepts of Contagion and Epidemics
Domestic Medicine
Germ Theory
Humoral Theory
International Sanitary Conferences
Medical Geography
Public Health
Vaccination

As always, if you are a U of R student or faculty and need help finding any of the materials listed in the bibliographies, contact me.

Thinking like a journalist…

Friday, November 20th, 2009

If you were a journalist and needed accurate, authoritative information about the flu, where would you go? Two different resources, it turns out, work well for both journalists and ESM/Disaster Science practicioners. Both offer well-researched and well-written overviews of the topic, in a layman-friendly fashion.

flu

CQ Researcher (available to the U of R community through Boatwright Memorial Library), offers a number of reports on topics dealing with the flu, including vaccine safety, emergency medicine, combating infectious diseases and, perhaps most relevant, one entitled, “Avian Flu Threat: Are we prepared for the next pandemic?” These reports are incredibly in-depth, giving the background, current situation and future outlook, as well as a bibliography, maps and charts, a chronology for the issue, and even contacts – people and groups who are SME’s on the material in question. My favorite part of a CQ Report, however, has to be the “Pro/Con” section, in which a question is asked relating to the topic. Two experts in the field, either from their testimony before Congress or in an essay written specifically for CQ, give their answer to the question. In the Avian Flu Threat report, for example, the question was, “Is there a serious risk of a human pandemic of avian flu?” The testimony of Michael T. Osterholm, Director of the Center for Infectious Disease Research and Policy at the University of Minnesota before the House Committee on International Relations answers the “pro” side of the question; Michael Fumento of the Hudson Institute, writing expressly for CQ, answered the “con” side.


Another resource, similarly aimed at giving background information to journalists, is the Nieman Center for Journalism at Harvard. Their “Covering Pandemic Flu” page offers a treasure trove of information. There’s an introduction, which includes the definition and etymology of the word “pandemic”, and an overview of the science behind the hype; pandemic preparedness at multiple levels, from individual to global; essays on the press coverage of flu, from veteran reporters in various countries; crisis communications information from Communications Directors at WHO and CDC; and finally, a history, glossary and bibliography of pandemic influenza. All the information has been developed and vetted by the Nieman Foundation, although links to other relevant material are offered.


PLoS Influenza page

Monday, August 24th, 2009

It’s a conundrum of modern publishing – how to achieve the high standards of “peer-review” in a timely manner. This is a particularly important issue when it comes to public health topics.

Take H1N1, for instance. What is the best way to quickly disseminate authoritative information about the disease? PLoS (Public Library of Science), a leader in open-access, peer-reviewed publishing, to the rescue!

PLoS Currents: Influenza, which we are launching today, is built on three key components: a small expert research community that PLoS is working with to run the website; Google Knol with new features that allow content to be gathered together in collections after being vetted by expert moderators; and a new, independent database at the National Center for Biotechnology Information (NCBI) called Rapid Research Notes, where research targeted for rapid communication, such as the content in PLoS Currents: Influenza will be freely and permanently accessible. To ensure that researchers are properly credited for their work, PLoS Currents content will also be given a unique identifier by the NCBI so that it is citable.”

While the postings are not subject to the same rigorous peer-review process as formally published scientific journals use, “inappropriate” submissions are being screened out by two experts in the fields of microbiology and infectious disease. While many of the articles listed are focused specifically on the biology of the virus, other topics can be found here as well, such as “Swine origin influenza A (H1N1) virus and ICU capacity in the US: Are we prepared?” and “Reducing influenza spreading over the airline network“, which uses different models to determine the most effective method for containing the spread of disease through air travel.

Frontloading

Friday, August 14th, 2009

I’m away next week, so I won’t be blogging, but this week has been a banner one for interesting items.

The National Library of Medicine maintains a collection of more than 30 environmental health websites under the auspices of the Environmental Health and Toxicology SIS (Specialized Information Services). Topics covered range from the specific (Health effects from the collapse of the World Trade Center) to the general (Tornadoes).  The links contained within each page vary, but most begin with a set of ‘Overview’ links, all from US Government sites, and then may go on to include links to glossaries, data and research sites, and law and policy. Almost all include links to specialized research from the National Library of Medicine’s databases, such as Pubmed, Toxline, Hazardous Substances Data Bank, ChemID Plus, Household Products Database, Tox Town and Medline Plus.

Disaster Medicine and Public Health Preparedness

Monday, August 3rd, 2009

While we’re on the topic of open-source public health items, this special supplement to the AMA’s journal “Disaster Medicine and Public Health Preparedness” (June 2009, Vol. 3) is freely available online. Article topics range from public policy (“National Strategy for Health Care System Preparedness”) to  Business Continuity (“Importance of Business Continuity in Health Care”) to NIMS (“Review of Hospital Preparedness Incidents to National Incident Management System Compliance”).

If you are interested in this topic and are a member of the University of Richmond community, you might want to check out our other Disaster Medicine journals, including the International Journal of Disaster Medicine, the Internet Journal of Rescue and Disaster Medicine, and Prehospital and Disaster Medicine. As always, let me know if you have any troubles viewing the links, or want to do a more refined search for a topic in this area.

Using summer to prepare for a possible H1N1 outbreak on campus

Tuesday, July 14th, 2009

This article, from Inside Higher Ed, is a nice overview of how several colleges and universities are using the summer to better prepare for an outbreak of H1N1 on campus. Seeing this prompted me to investigate what our campus has done about H1N1, as Virginia is one of the handful of states with a recorded “widespread” outbreak.

This follows last month’s H1N1 Summit, hosted at the National Institutes of Health. I can’t seem to find an archived copy of the webcast, which was streamed live, but this blog post by J. Solomon (“In case of emergency, read blog…”) gives a great overview and links to video from several key speakers.

Swine Flu Resources Round-up

Thursday, May 28th, 2009

It’s been interesting to watch publishers open up their H1N1 articles and resources to the general public. (Disclaimer: I know that part is only interesting to me as a librarian.  But the question remains: Is the future of publishing a ‘hybrid’ open-source model? Hmmm….)

Here’s a summary:

  • Scientific American mainly sums up blog entries from the “60 Second Science” blog. But there’s also a detailed interview transcript with Dr. Chris Olsen, Director of the Olsen Laboratory, a veterinary medicine lab in Wisconsin where Influenza ‘A’ viruses are studied, and a link to the April 2009 cover story called, “How to Prevent the Next Pandemic” that describes the work of the Global Viral Forecasting Initiative.
  • The Lancet (a British medical journal) has also opened their pages:

“The Lancet’s H1N1 Resource Centre is the result of a collaborative effort by the editors of over 40 Elsevier-published journals and 11 learned societies who have agreed to make freely available on this site any relevant content. All papers have been selected by a Lancet editor, grouped by topic and fulltext pdfs made available to download free of charge.”

(If you haven’t seen an Elsevier price quote, you can’t appreciate the magnitude of this – Elsevier articles are notoriously expensive.)

Biographies of Disease: Influenza

Wednesday, May 13th, 2009

This title, from a set we’re collecting, caught my eye.

From the Series Foreward:

Every disease has a story to tell: about how it started long ago and began to disable or even take the lives of its innocent victims, about the way it hurts us, and about how we are trying to stop it. In this Biographies of Disease series, the authors tell the stories of the diseases that we have come to know and dread…

This is the biography of a disease, but it is also the story of real people who made incredible sacrifices to stop it in its tracks.”

The author of the Influenza volume, Roni K. Devlin, is a practicing physician with a sub-specialty in Infectious Diseases. She covers the topic of influenza in a way that is both thorough and engaging. Starting with an explanation of “germ theory”, six chapters detail everything from the makeup and discovery of the virus, the epidemiology of influenza, particularly how it relates to H5N1 (avian flu – remember this was published before swine flu became all the rage), to the pandemic of 1918. But this is not solely a history book (try “The Great Influenza” by John M. Barry, or “Flu” by Gina Kolata for that). The last three chapters detail the clinical ‘manifestations’ of the flu, methods of diagnosis, future research possibilities, and prevention and treatment options.

In addition, this slim volume is replete with tables, illustrations, and other useful details, including a timeline going back to Hippocrates, a glossary, and a bibiliography with many references to online resources. Swine flu merits a fairly long entry in the index. Altogether, this is an accessible but scholarly resource. It’s Library of Congress Subject Heading is “Influenza–History–Popular Works”, but that doesn’t begin to touch the science detailed in it. Check it out!

Virginia Emergency Operations Plans link

Thursday, May 7th, 2009

From the VDEM newsletter:

Gov. Tim Kaine has approved the Commonwealth of Virginia Emergency Operations Plan Pandemic Influenza Incident Annex VI, now available at http://www.vaemergency.com/library/plans/index.cfm. The annex represents nearly two years of collaboration with many state agencies and provides guidance for non-medical response operations in Virginia to a pandemic influenza event.